SCHEMBL7690238

SCHEMBL7690238

CCCCS(=O)(=O)Oc1ccc(S(=O)(=O)C(=[N+]=[N-])S(=O)(=O)c2ccc(OC(C)(C)C)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 5/20 0.39
MMP14 P50281 5/20 0.39
MMP9 P14780 4/20 0.39
MMP7 P09237 2/20 0.39
CA12 O43570 3/20 0.35
CA2 P00918 3/20 0.35
ALPL P05186 3/20 0.34
ALPI P09923 3/20 0.34
ENPP3 O14638 1/20 0.34
ENPP1 P22413 1/20 0.34
ENPP2 Q13822 1/20 0.34
CA1 P00915 1/20 0.33
TSHR P16473 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
MMP13 P45452 2/20 0.32
JAK1 P23458 1/20 0.32
MMP1 P03956 2/20 0.32
ADAMTS4 O75173 1/20 0.32
ADAMTS5 Q9UNA0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7690031 0.92 MMP2 (0.44) MMP2MMP14MMP9MMP7CA12
SCHEMBL7695981 0.89 MMP2 (0.39) MMP2MMP14MMP9MMP7CA12
SCHEMBL7690236 0.88 MRGPRX1 (0.32) MMP2MMP14MMP9MMP7
SCHEMBL7690710 0.88 STS (0.40) MMP2MMP14MMP9MMP7CA12
SCHEMBL7693670 0.88 MMP2 (0.40) MMP2MMP14MMP9MMP7CA12
SCHEMBL7695879 0.87 MMP2 (0.41) MMP2MMP14MMP9MMP7CA12
SCHEMBL7692524 0.87 MMP2 (0.41) MMP2MMP14MMP9MMP7CA12
SCHEMBL7696505 0.85 MMP2 (0.41) MMP2MMP14MMP9MMP7CA12
SCHEMBL7696010 0.85 MMP2 (0.37) MMP2MMP14MMP9MMP7ALPL
SCHEMBL7690175 0.85 MMP2 (0.50) MMP2MMP14MMP9MMP7CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6338931-B1 PHOTOACID GENERATOR OF SULFONYLDIAZOMETHANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-01-15 US disclosed