Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB2 | Q9UBS0 | 8/20 | 0.60 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690357 | 0.99 | RPS6KB2 (0.61) | RPS6KB2SRPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7690349 | 0.85 | RPS6KB2 (0.60) | RPS6KB2SRPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7691270 | 0.77 | TDP1 (0.54) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL7693467 | 0.76 | SNCA (0.38) | RPS6KB2SRPK1ALDH1A1HSD17B10SNCA | |
| SCHEMBL7692571 | 0.76 | RPS6KB2 (1.00) | RPS6KB2SRPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7691277 | 0.76 | TDP1 (0.55) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL31060401 | 0.75 | RPS6KB2 (1.00) | RPS6KB2SRPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL1905308 | 0.74 | NPC1 (0.62) | RPS6KB2SRPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL7693473 | 0.74 | SNCA (0.38) | RPS6KB2SRPK1ALDH1A1HSD17B10SNCA | |
| SCHEMBL7692726 | 0.73 | KDM4E (0.51) | ALDH1A1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | claimed |
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |