Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693473 | 0.99 | SNCA (0.38) | SNCAALDH1A1CYP2C9CYP2C19CASP6 | |
| SCHEMBL7693469 | 0.85 | CA2 (0.36) | CSNK2A2CSNK2BCA2CA9CA12 | |
| SCHEMBL7691270 | 0.80 | TDP1 (0.54) | SNCAALDH1A1CYP2C9CYP2C19CASP6 | |
| SCHEMBL7691277 | 0.79 | TDP1 (0.55) | SNCAALDH1A1CYP2C9CYP2C19CASP6 | |
| SCHEMBL7690347 | 0.76 | RPS6KB2 (0.60) | SNCAALDH1A1CYP2C9CYP2C19CASP6 | |
| SCHEMBL7692865 | 0.74 | PDGFRB (0.53) | ALDH1A1BACE1TDP1GPBAR1PDGFRB | |
| SCHEMBL7690357 | 0.74 | RPS6KB2 (0.61) | SNCAALDH1A1CYP2C9CYP2C19CASP6 | |
| SCHEMBL28069979 | 0.72 | SNCA (0.56) | SNCAALDH1A1CYP2C9CYP2C19CASP6 | |
| SCHEMBL836622 | 0.72 | SNCA (0.60) | SNCAALDH1A1CYP2C9CYP2C19CASP6 | |
| SCHEMBL3101290 | 0.72 | SNCA (0.60) | SNCAALDH1A1CYP2C9CYP2C19CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | claimed |
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |