Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690413 | 0.83 | HPGD (0.54) | HPGDHTTMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7697093 | 0.82 | SMN1; SMN2 (0.54) | HPGDHTTGRM5MAPTKMT2A | |
| SCHEMBL7692590 | 0.82 | HTT (0.51) | HPGDHTTGRM5KMT2AMEN1 | |
| SCHEMBL7696122 | 0.81 | HPGD (0.43) | HPGDHTTMAPTGAASMN1; SMN2 | |
| SCHEMBL7697610 | 0.80 | ABCG2 (0.50) | HPGDHTTMAPTKMT2AMEN1 | |
| SCHEMBL7691393 | 0.80 | LMNA (0.54) | HPGDGRM5MAPTKMT2AMEN1 | |
| SCHEMBL7695575 | 0.76 | HTT (0.54) | HPGDHTTMAPTKMT2AMEN1 | |
| SCHEMBL7696074 | 0.76 | NPC1 (0.74) | HPGDHTTMAPTKMT2AMEN1 | |
| SCHEMBL30517179 | 0.74 | HPGD (0.50) | HPGDHTTMAPTKMT2AMEN1 | |
| SCHEMBL30517180 | 0.74 | HPGD (0.50) | HPGDHTTMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |