SCHEMBL7690628

SCHEMBL7690628

CCCCOc1c(C)cccc1C(=O)N1CCN(Cc2cnc(C)n2Cc2ccc(C#N)c(Oc3cccc(C)n3)c2)CC1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FNTA P49354 6/20 0.42
FNTB P49356 6/20 0.42
PGGT1B P53609 5/20 0.42
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
TLR7 Q9NYK1 1/20 0.34
POLB P06746 2/20 0.34
LMNA P02545 2/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
FFAR4 Q5NUL3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7683704 0.93 FNTA (0.44) FNTAFNTBPGGT1BMEN1KMT2A
SCHEMBL7689759 0.92 FNTA (0.46) FNTAFNTBPGGT1BMEN1KMT2A
SCHEMBL7690256 0.90 FNTA (0.42) FNTAFNTBPGGT1BMEN1KMT2A
SCHEMBL7688311 0.90 FNTA (0.42) FNTAFNTBPGGT1BMEN1KMT2A
SCHEMBL7681530 0.88 FNTA (0.43) FNTAFNTBPGGT1BMEN1KMT2A
SCHEMBL7621675 0.88 FNTA (0.46) FNTAFNTBPGGT1BMEN1KMT2A
SCHEMBL7690275 0.87 FNTA (0.47) FNTAFNTBPGGT1BMEN1KMT2A
SCHEMBL7685750 0.87 FNTA (0.47) FNTAFNTBPGGT1BMEN1KMT2A
SCHEMBL7683732 0.84 FNTA (0.44) FNTAFNTBPGGT1BMEN1KMT2A
SCHEMBL7626193 0.82 FNTA (0.47) FNTAFNTBPGGT1BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020052363-A1 Inhibitors of prenyl-protein transferase DINSMORE CHRISTOPHER J (US) 2002-05-02 US claimed
WO-2001060369-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2001-08-23 WO claimed
US-20020052363-A1 Inhibitors of prenyl-protein transferase DINSMORE CHRISTOPHER J (US) 2002-05-02 US disclosed
WO-2001060369-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2001-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052363-A1 Inhibitors of prenyl-protein transferase FNTA, FNTB, PTAR1 FNTA 1/4885FNTB 2/4885PGGT1B 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.