Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210041 | 0.81 | SMN1; SMN2 (0.47) | ALOX5MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27512055 | 0.79 | SMN1; SMN2 (0.54) | ALOX5MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27935499 | 0.78 | NAPRT (0.50) | ALOX5MAPTSMN1; SMN2NPC1RAB9A | |
| Benzene SCHEMBL28977956 | 0.78 | SMN1; SMN2 (0.70) | MAPTSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL57554 | 0.78 | SMN1; SMN2 (0.70) | MAPTSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL6964944 | 0.74 | SMN1; SMN2 (0.58) | MAPTSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL616739 | 0.73 | PTPN11 (0.75) | SMN1; SMN2NPC1RAB9APKMTP53 | |
| Hydrazine SCHEMBL28432690 | 0.73 | SMN1; SMN2 (0.64) | MAPTSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL3192618 | 0.72 | POLB (0.50) | ALOX5MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29742566 | 0.72 | PTPN11 (0.72) | SMN1; SMN2NPC1RAB9APKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020007071-A1 | Benzimidzolyl neuropeptide Y receptor antagonists | BRITTON THOMAS CHARLES (US) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007071-A1 | Benzimidzolyl neuropeptide Y receptor antagonists | NPY1R, NPY2R, NPY5R | ALOX5 1548/4885MAPT 3175/4885SMN1; SMN2 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.