Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | CDK9 | P50750 | 1/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580396 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Benzene SCHEMBL28977956 | 0.85 | SMN1; SMN2 (0.70) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL57554 | 0.85 | SMN1; SMN2 (0.70) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL9856061 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL9363961 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL616739 | 0.80 | PTPN11 (0.75) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL992038 | 0.80 | EPHX2 (0.64) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Hydrazine SCHEMBL28432690 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL2680094 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL12724395 | 0.79 | RAB9A (0.54) | SMN1; SMN2TP53EPHX1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |