Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690669 | 1.00 | MAPT (0.39) | MAPTTSHRL3MBTL1ALDH1A1CA9 | |
| SCHEMBL7684744 | 0.95 | MAPT (0.39) | MAPTL3MBTL1ALDH1A1CA9KCNN4 | |
| SCHEMBL7684749 | 0.95 | MAPT (0.39) | MAPTL3MBTL1ALDH1A1CA9KCNN4 | |
| SCHEMBL7979224 | 0.94 | MAPT (0.38) | MAPTL3MBTL1ALDH1A1CA9KCNN4 | |
| SCHEMBL7979226 | 0.94 | MAPT (0.38) | MAPTL3MBTL1ALDH1A1CA9KCNN4 | |
| SCHEMBL8121707 | 0.94 | MAPT (0.38) | MAPTTSHRL3MBTL1ALDH1A1CA9 | |
| SCHEMBL7683865 | 0.94 | KMT2A (0.39) | MAPTTSHRL3MBTL1ALDH1A1CA9 | |
| SCHEMBL8121711 | 0.94 | MAPT (0.38) | MAPTTSHRL3MBTL1ALDH1A1CA9 | |
| SCHEMBL7683867 | 0.94 | KMT2A (0.39) | MAPTTSHRL3MBTL1ALDH1A1CA9 | |
| SCHEMBL7684171 | 0.93 | MAPT (0.42) | MAPTTSHRL3MBTL1ALDH1A1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137929-A1 | 1 - (3-heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | INTELLECTUAL PROPERTY DEPARTMENT, BASF AKTIENGESELLSCHAFT (DE) | 2002-09-26 | — | — | US | disclosed |
| US-6303783-B1 | 1- (3-Heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | AMERICAN CYANAMID CO. | 2001-10-16 | — | — | US | disclosed |
| EP-0985670-A1 | 1-(3-Heterocyclylphenyl)isothiourea, -isourea, -guanidine and -amidine compounds as herbicides | American Cyanamid Company (US) | 2000-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137929-A1 | 1 - (3-heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | IMPDH1, GANC, DDT | MAPT 3732/4885TSHR 1071/4885L3MBTL1 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.