Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979224 | 1.00 | MAPT (0.38) | MAPTSLC5A1SLC5A2L3MBTL1CA9 | |
| SCHEMBL7684744 | 0.94 | MAPT (0.39) | MAPTSLC5A1SLC5A2L3MBTL1CA9 | |
| SCHEMBL7690669 | 0.94 | MAPT (0.39) | MAPTSLC5A1SLC5A2L3MBTL1CA9 | |
| SCHEMBL7684749 | 0.94 | MAPT (0.39) | MAPTSLC5A1SLC5A2L3MBTL1CA9 | |
| SCHEMBL7690667 | 0.94 | MAPT (0.39) | MAPTSLC5A1SLC5A2L3MBTL1CA9 | |
| SCHEMBL8121707 | 0.93 | MAPT (0.38) | MAPTSLC5A1SLC5A2L3MBTL1CA9 | |
| SCHEMBL7683865 | 0.93 | KMT2A (0.39) | MAPTSLC5A1SLC5A2L3MBTL1CA9 | |
| SCHEMBL7684518 | 0.93 | CA9 (0.44) | MAPTSLC5A1SLC5A2L3MBTL1CA9 | |
| SCHEMBL8121711 | 0.93 | MAPT (0.38) | MAPTSLC5A1SLC5A2L3MBTL1CA9 | |
| SCHEMBL7683867 | 0.93 | KMT2A (0.39) | MAPTSLC5A1SLC5A2L3MBTL1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303783-B1 | 1- (3-Heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | AMERICAN CYANAMID CO. | 2001-10-16 | — | — | US | disclosed |
| EP-0985670-A1 | 1-(3-Heterocyclylphenyl)isothiourea, -isourea, -guanidine and -amidine compounds as herbicides | American Cyanamid Company (US) | 2000-03-15 | — | — | EP | disclosed |