SCHEMBL7690938

SCHEMBL7690938

CC/C(=N\OCc1ccccc1)OCc1ccccc1O/C(=C/OC)C(=O)OC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.34
TSHR P16473 1/20 0.33
RAB9A P51151 3/20 0.32
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
NPC1 O15118 2/20 0.32
PTGER4 P35408 1/20 0.32
PTGER3 P43115 1/20 0.32
PTGER2 P43116 1/20 0.32
ITGA4 P13612 1/20 0.31
ITGB7 P26010 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
HRH1 P35367 1/20 0.31
MIF P14174 1/20 0.31
ALDH1A1 P00352 2/20 0.31
POLB P06746 2/20 0.31
HCAR2 Q8TDS4 1/20 0.31
MBTPS1 Q14703 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7690941 1.00 HIF1A (0.34) HIF1ATSHRRAB9AKMT2AMEN1
SCHEMBL7690943 0.92 HIF1A (0.35) HIF1ATSHRRAB9AKMT2AMEN1
SCHEMBL8502333 0.82 HIF1A (0.41) HIF1ATSHRL3MBTL1ALDH1A1MAPT
SCHEMBL8505441 0.82 HIF1A (0.41) HIF1ATSHRL3MBTL1ALDH1A1MAPT
SCHEMBL8026204 0.75 PPARG (0.44) RAB9ANPC1L3MBTL1SMN1; SMN2
SCHEMBL8026203 0.75 PPARG (0.44) RAB9ANPC1L3MBTL1SMN1; SMN2
SCHEMBL7694443 0.74 NPSR1 (0.44) KMT2AMEN1L3MBTL1ALDH1A1POLB
SCHEMBL7694445 0.74 NPSR1 (0.44) KMT2AMEN1L3MBTL1ALDH1A1POLB
SCHEMBL7754320 0.73 KMT2A (0.44) RAB9AKMT2AMEN1NPC1ALDH1A1
SCHEMBL7801127 0.73 ALDH1A1 (0.49) TSHRRAB9AKMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337306-B1 HERBICIDES FOR AGRICULTURE RHONE-POULENC AGRO (FR) 2002-01-08 US disclosed
EP-0961766-A1 PHENOXYACETIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES Rhone Poulenc Agro (FR) 1999-12-08 EP disclosed
WO-1998034898-A1 PHENOXYACETIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES RHONE-POULENC AGRO (FR) 1998-08-13 WO disclosed