Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694470 | 0.95 | PPARG (0.36) | PPARGPPARAMAPTKMT2AKDM4E | |
| SCHEMBL7692449 | 0.89 | PPARG (0.38) | PPARGPPARAKMT2AKDM4EALDH1A1 | |
| SCHEMBL2104678 | 0.86 | CYP2C9 (0.47) | KMT2AKDM4EL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL15353192 | 0.84 | KDM4E (0.47) | PPARGPPARAMAPTKMT2AKDM4E | |
| SCHEMBL15352972 | 0.84 | KDM4E (0.47) | PPARGPPARAMAPTKMT2AKDM4E | |
| SCHEMBL27715914 | 0.83 | CYSLTR2 (0.42) | PPARGPPARAMAPTKMT2AKDM4E | |
| SCHEMBL22288177 | 0.83 | KMT2A (0.38) | PPARGPPARAMAPTKMT2AKDM4E | |
| SCHEMBL7691846 | 0.82 | ALDH1A1 (0.40) | MAPTKMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL11379720 | 0.82 | CYSLTR2 (0.41) | PPARGPPARAMAPTKMT2AKDM4E | |
| SCHEMBL1610202 | 0.82 | PPARG (0.35) | PPARGPPARAMAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |