SCHEMBL7691111

SCHEMBL7691111

CCN(CC)c1c(Cl)cc(N)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.44
ALDH1A1 P00352 6/20 0.44
L3MBTL1 Q9Y468 3/20 0.41
TSHR P16473 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
PSMD14 O00487 1/20 0.41
MAPK1 P28482 1/20 0.41
RECQL P46063 1/20 0.41
GFER P55789 1/20 0.41
KDM4E B2RXH2 3/20 0.41
KMT2A Q03164 2/20 0.41
THRB P10828 1/20 0.41
GAA P10253 2/20 0.40
PGK1 P00558 1/20 0.40
S100B P04271 1/20 0.35
TP53 P04637 1/20 0.35
CRHR1 P34998 2/20 0.34
CHRM2 P08172 1/20 0.34
CHRM3 P20309 1/20 0.34
MAOA P21397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7692200 0.83 CYP3A4 (0.41) CYP3A4ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL8577057 0.73 ALDH1A1 (0.50) CYP3A4ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL7692209 0.73 GAA (0.44) CYP3A4ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL5950905 0.72 CYP3A4 (0.47) CYP3A4ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL11045130 0.72 CYP3A4 (0.39) CYP3A4ALDH1A1TSHRTHRBTP53
SCHEMBL11033722 0.72 CYP3A4 (0.39) CYP3A4ALDH1A1TSHRTHRBTP53
Hydrochloric Acid SCHEMBL4836696 0.71 CYP3A4 (0.45) CYP3A4ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL10614284 0.71 HSP90AA1 (0.41) ALDH1A1TSHRTDP1MAPK1KMT2A
SCHEMBL9146759 0.70 KDM4E (0.31) L3MBTL1TDP1KDM4EKMT2AGAA
SCHEMBL9427818 0.70 ALDH1A1 (0.53) ALDH1A1L3MBTL1TSHRKMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6340596-B1 COLORIMETRIC ANALYSIS; REACTING HYDROGEN SULFIDE WITH P-(DIALKYLAMINO)-ANILINE DERIVATIVE AND OXIDIZING AGENT UNDER ACIDIC CONDITIONS FUJIREBIO INC. (JP) 2002-01-22 US claimed
US-6340596-B1 COLORIMETRIC ANALYSIS; REACTING HYDROGEN SULFIDE WITH P-(DIALKYLAMINO)-ANILINE DERIVATIVE AND OXIDIZING AGENT UNDER ACIDIC CONDITIONS FUJIREBIO INC. (JP) 2002-01-22 US disclosed
EP-0936466-A2 Reagent composition for measuring hydrogen sulfide and method for measuring hydrogen sulfide FUJIREBIO INC. (JP) 1999-08-18 EP disclosed
US-5310724-A Pre- and postemergence; plant growth regulators FMC CORPORATION (US) 1994-05-10 US disclosed
US-5108486-A Herbicides KANAGAWA CHEMICAL LABORATORY, LTD. (JP) 1992-04-28 US disclosed