Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768943 | 0.84 | CCNC (0.36) | MCHR1HRH3SLC2A1CCR2 | |
| SCHEMBL769116 | 0.84 | MCHR1 (0.34) | MCHR1DRD2ADRB2CHRM3SLC2A1 | |
| SCHEMBL381592 | 0.83 | CHRM3 (0.51) | CHRM3SLC2A1 | |
| SCHEMBL768844 | 0.83 | HDAC6 (0.34) | HTR1ADRD2HRH3 | |
| SCHEMBL768103 | 0.82 | HRH3 (0.41) | NPC1HTR1ADRD2MTORRAB9A | |
| Hydrochloric Acid SCHEMBL768511 | 0.82 | JAK1 (0.34) | HRH3CCR2 | |
| SCHEMBL767767 | 0.81 | HRH3 (0.41) | NPC1HTR1ADRD2MTORRAB9A | |
| SCHEMBL768533 | 0.81 | HRH3 (0.41) | NPC1HTR1ADRD2MTORRAB9A | |
| SCHEMBL768439 | 0.81 | CHRM2 (0.39) | MCHR1HRH3ADRB2CHRM3SLC2A1 | |
| SCHEMBL768889 | 0.81 | CHRM2 (0.39) | MCHR1HRH3ADRB2CHRM3SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | CHRM3, CHRM2, TACR2 | MCHR1 239/4885NPC1 1488/4885HTR1A 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.