Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095640 | 0.84 | S1PR1 (0.44) | ABL1ALDH1A1NR1H2NR1H3NR1I2 | |
| SCHEMBL7695223 | 0.81 | S100B (0.43) | ABL1ALDH1A1SLC16A3SLC16A1KDM4E | |
| SCHEMBL10340842 | 0.80 | KDM4E (0.37) | ABL1ALDH1A1SLC16A3SLC16A1KDM4E | |
| SCHEMBL7689100 | 0.78 | AR (0.48) | ALDH1A1NR1H2NR1H3SLC16A3SLC16A1 | |
| SCHEMBL23961647 | 0.76 | MEN1 (0.40) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL10776318 | 0.76 | S1PR1 (0.48) | ALDH1A1HPGDNR1H2NR1H3NR1I2 | |
| SCHEMBL1459455 | 0.75 | EGFR (0.44) | ALDH1A1NR1H2NR1H3EGFRERBB2 | |
| SCHEMBL15871096 | 0.74 | CYP1A2 (0.42) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL1815516 | 0.73 | CNR2 (0.46) | EGFRERBB2CNR2 | |
| SCHEMBL12677177 | 0.73 | CNR2 (0.46) | EGFRERBB2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335446-B1 | Quinolinium- and pyridinium-based fluorescent dye compounds | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2002-01-01 | — | — | US | disclosed |