SCHEMBL769152

SCHEMBL769152

CC(C)(C)CC(C)(C)c1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)c2ccccc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
ESR1 P03372 1/20 0.34
TP53 P04637 1/20 0.34
PGR P06401 1/20 0.34
CYP3A4 P08684 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
AR P10275 1/20 0.34
MAPT P10636 1/20 0.34
DRD1 P21728 1/20 0.34
PTGS1 P23219 1/20 0.34
SLC6A2 P23975 1/20 0.34
PDE4A P27815 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
SLC6A4 P31645 1/20 0.34
OPRM1 P35372 1/20 0.34
DRD3 P35462 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377561 1.00 NPC1 (0.38) NPC1RAB9AMEN1USP2ESR1
SCHEMBL29353178 0.90 NPC1 (0.40) NPC1RAB9AESR1CYP3A4MAPT
SCHEMBL76991 0.90 NPC1 (0.40) NPC1RAB9AESR1CYP3A4MAPT
Benzotriazole SCHEMBL7895570 0.90 NPC1 (0.33) NPC1RAB9A
SCHEMBL22080467 0.90 SHBG (0.36) NPC1RAB9AESR1CYP3A4IDH1
SCHEMBL29358618 0.89 NPC1 (0.42) NPC1RAB9AMEN1ESR1TP53
SCHEMBL768704 0.89 NPC1 (0.42) NPC1RAB9AMEN1ESR1TP53
SCHEMBL30510201 0.89 CYP3A4 (0.38) NPC1RAB9AMEN1USP2ESR1
SCHEMBL8861277 0.89 CYP3A4 (0.38) NPC1RAB9AMEN1USP2ESR1
SCHEMBL7787049 0.89 NPC1 (0.34) NPC1RAB9AESR1CYP3A4IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 540 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7288583-B2 Method of content protection with durable UV absorbers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-10-30 US claimed
US-20050123691-A1 Photo-cured and stabilized coatings SUHADOLNIK JOSEPH (US) 2005-06-09 US claimed
US-20040191447-A1 storage of food, beverages, drugs or cosmetics in radiation transparent plastic containers having coatings comprising stabilizer agents selected from hydroxyphenyl benzotriazole ultraviolet radiation absorber materials ANDREWS STEPHEN M (US) 2004-09-30 US claimed
US-6797751-B2 A CLEAR OR LIGHTLY COLORED PLASTIC CONTAINERS OR FILMS COMPRISING A BENZOTRIAZOLES OR TRIS-ARYL-S-TRIAZINES STABILIZER; PROTECTIVE DEVICES FOR FOODS, BEVERAGES, DRUGS, COSMETICS, SHAMPOO CIBA SPECIALTY CHEMICALS CORPORATION 2004-09-28 US claimed
EP-1448613-A1 CURABLE MIXTURES COMPRISING UV-ABSORBER, ACYLPHOSPHINOXIDE AND HYDROXY KETONE PHOTOINITIATOR Ciba SC Holding AG (CH) 2004-08-25 EP claimed
US-20030144389-A1 Method of content protection with durable UV absorbers ANDREWS STEPHEN MARK (US) 2003-07-31 US claimed
US-20030139499-A1 Photo-cured and stabilized coatings CIBA SPECIALTY CHEMICALS CORP. 2003-07-24 US claimed
US-20030119950-A1 Method of content protection with durable UV absorbers ANDREWS STEPHEN MARK (US) 2003-06-26 US claimed
WO-2003046017-A1 CURABLE MIXTURES COMPRISING UV-ABSORBER ACYLPHOSPHINOXIDE AND HYDROXY KETONE PHOTOINITIATOR CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-06-05 WO claimed
US-20020028861-A1 Method of content protection with durable UV absorbers CIBA SPECIALTY CHEMICALS CORP. 2002-03-07 US claimed
US-6296674-B1 Candle wax stabilized with red-shift benzotriazoles CIBA SPECIALTY CHEMICALS CORPORATION 2001-10-02 US claimed
US-6268415-B1 POLYMERS AND STABILIZERS FOR ENHANCED STABILITY CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-31 US claimed
EP-4008210-B1 A KNIT TEXTILE NIKE INNOVATE CV (US) 2025-08-27 EP disclosed
EP-4511337-A2 LOW-VOLATILITY RADIATION CURABLE COMPOSITIONS FOR COATING OPTICAL FIBERS Covestro (Netherlands) B.V. (NL) 2025-02-26 EP disclosed
EP-4511336-A1 RADIATION CURABLE COMPOSITIONS FOR COATING OPTICAL FIBERS Covestro (Netherlands) B.V. (NL) 2025-02-26 EP disclosed
EP-3833206-B1 SOLE STRUCTURE OF AN ARTICLE OF FOOTWEAR INCLUDING MESH NIKE INNOVATE CV (US) 2024-11-06 EP disclosed
EP-1038912-A2 High molecular weight hindered hydrocarbyloxyamine stabilizers Ciba SC Holding AG (CH) 2000-09-27 EP disclosed
WO-2000043376-A1 ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-07-27 WO disclosed
US-6040455-A REACTING A HALOBENZOTRIAZOLE COMPOUND WITH ALIPHATIC, PHENYLALKYL OR ARYL MERCAPTAN COMPOUND TO FORM 5-THIO SUBSTITUTED BENZOTRIAZOLE, OXIDIZING WITH HYDROGEN PEROXIDE TO FOR 5-SULFONE SUBSTITUED BENZOTRIAZOLE COMPOUND CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-03-21 US disclosed
US-5977219-A Benzotriazole UV absorbers having enhanced durability CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-11-02 US disclosed