Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691704 | 1.00 | TDP1 (0.56) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL2221785 | 0.96 | TDP1 (0.60) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL9952787 | 0.96 | TDP1 (0.60) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL9952791 | 0.96 | TDP1 (0.60) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL9952834 | 0.96 | TDP1 (0.60) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL2221782 | 0.96 | TDP1 (0.60) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL9952829 | 0.96 | TDP1 (0.60) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL9952736 | 0.96 | TDP1 (0.60) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL9952732 | 0.96 | TDP1 (0.60) | TDP1POLBAPEX1HTTLMNA | |
| SCHEMBL9951812 | 0.95 | TDP1 (0.57) | TDP1POLBAPEX1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335409-B1 | LIQUID CRYSTAL ORIENTATION | ROLIC AG (CH) | 2002-01-01 | — | — | US | disclosed |
| US-6107427-A | Cross-linkable, photoactive polymer materials | ROLIC AG (CH) | 2000-08-22 | — | — | US | disclosed |