Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447785 | 0.86 | ABCB1 (0.34) | HDAC1DAGLAABCB1SLC6A2SLC6A4 | |
| SCHEMBL7447779 | 0.86 | ABCB1 (0.34) | HDAC1DAGLAABCB1SLC6A2SLC6A4 | |
| SCHEMBL7408391 | 0.78 | ALDH1A1 (0.43) | HDAC1ALDH1A1 | |
| SCHEMBL7452364 | 0.78 | ALDH1A1 (0.43) | HDAC1ALDH1A1 | |
| SCHEMBL7404869 | 0.76 | TSHR (0.36) | HDAC1DAGLAABCB1ALDH1A1 | |
| SCHEMBL7454510 | 0.76 | TSHR (0.36) | HDAC1DAGLAABCB1ALDH1A1 | |
| SCHEMBL7451704 | 0.73 | ABCB1 (0.33) | HDAC1DAGLAABCB1ALDH1A1 | |
| SCHEMBL7451706 | 0.73 | ABCB1 (0.33) | HDAC1DAGLAABCB1ALDH1A1 | |
| SCHEMBL7458431 | 0.71 | HSD17B10 (0.34) | DAGLAABCB1 | |
| SCHEMBL7449060 | 0.71 | HSD17B10 (0.34) | DAGLAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495699-B2 | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | AGOURON PHARMACEUTICALS INC. | 2002-12-17 | — | — | US | disclosed |