Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191551 | 0.79 | GRM4 (0.41) | LMNAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL17291109 | 0.78 | MAPT (0.38) | PKMLMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL14579653 | 0.78 | TLR2 (0.44) | LMNAMEN1KMT2AESR1ESR2 | |
| SCHEMBL3437822 | 0.76 | CYP2A6 (0.30) | CYP2A6 | |
| SCHEMBL10209572 | 0.76 | ALDH1A1 (0.30) | LMNAALDH1A1CYP2A6 | |
| SCHEMBL9657539 | 0.76 | ERN1 (0.34) | MEN1KMT2AESR1TYMSALDH1A1 | |
| SCHEMBL27398971 | 0.76 | CYP1A2 (0.52) | MEN1KMT2AESR1ESR2ALDH1A1 | |
| SCHEMBL9050322 | 0.75 | ERN1 (0.37) | LMNAMEN1KMT2AALDH1A1CYP2A6 | |
| SCHEMBL2946 | 0.75 | ALDH1A1 (0.47) | L3MBTL1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL28814017 | 0.73 | ALDH1A1 (0.46) | L3MBTL1MEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024619-A1 | AMINE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 2002-03-28 | — | — | WO | disclosed |