Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27282486 | 1.00 | NPSR1 (0.43) | NPSR1GLO1ALDH1A1TSHRHCAR2 | |
| SCHEMBL28431641 | 0.84 | TSHR (0.43) | ALDH1A1TSHRHCAR2HSD17B10SMN1; SMN2 | |
| SCHEMBL10411106 | 0.81 | NPSR1 (0.59) | NPSR1GLO1ALDH1A1TSHRHCAR2 | |
| SCHEMBL15132873 | 0.79 | HCAR2 (0.39) | NPSR1GLO1ALDH1A1TSHRHCAR2 | |
| SCHEMBL28014183 | 0.79 | TSHR (0.60) | NPSR1ALDH1A1TSHRHCAR2HSD17B10 | |
| SCHEMBL17269614 | 0.79 | GLO1 (0.47) | NPSR1GLO1ALDH1A1TSHRHCAR2 | |
| SCHEMBL27301100 | 0.79 | NPSR1 (0.45) | NPSR1GLO1ALDH1A1TSHRHCAR2 | |
| SCHEMBL27469964 | 0.78 | TSHR (0.55) | NPSR1ALDH1A1TSHRHCAR2LMNA | |
| SCHEMBL23953799 | 0.77 | NPSR1 (0.43) | NPSR1GLO1ALDH1A1TSHRHCAR2 | |
| SCHEMBL18924027 | 0.77 | GLO1 (0.40) | NPSR1GLO1ALDH1A1TSHRHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011142716-A1 | NOVEL HEMIFUMARATE SALT OF ISOINDOLE COMPOUND ACTING AS BACE INHIBITOR | ASTRAZENECA AB (SE) | 2011-11-17 | — | — | WO | disclosed |