Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.88 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | PPARG | P37231 | 2/20 | 0.73 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.73 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 2/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.67 |
| ▸ | CA2 | P00918 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691829 | 0.78 | HPGD (0.91) | GFERHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL14563911 | 0.77 | GFER (0.69) | GFERHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL5434943 | 0.77 | ALDH1A1 (0.76) | GFERHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL7694437 | 0.74 | HPGD (0.71) | HPGDKDM4EALDH1A1KMT2APPARG | |
| SCHEMBL7072642 | 0.74 | ALDH1A1 (0.81) | GFERHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL13983998 | 0.72 | BCHE (0.67) | GFERHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL8978563 | 0.72 | APOBEC3G (1.00) | GFERHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL20986874 | 0.72 | TDP1 (0.69) | GFERHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL8978622 | 0.72 | HPGD (0.79) | GFERHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL7694498 | 0.72 | CA12 (0.70) | GFERHPGDKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066447-A1 | 4H-1,2,4-TRIAZOLE-3(2H)-THIONE DERATIVES AS SPHINGOMYELINASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |