Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | DHFR | P00374 | 2/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14164087 | 0.87 | CA1 (0.78) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL7694816 | 0.86 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL7691806 | 0.85 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL22758024 | 0.78 | CA1 (0.71) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL22758022 | 0.78 | CA1 (0.71) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL31383367 | 0.78 | CA1 (0.71) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL7696813 | 0.78 | ALDH1A1 (0.81) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL10113664 | 0.76 | CA1 (0.78) | ALDH1A1KMT2AMEN1LMNAALOX12 | |
| SCHEMBL19752654 | 0.76 | POLB (0.74) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL2951080 | 0.76 | POLB (0.74) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |