Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100738 | 0.85 | MAPT (0.45) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL5101243 | 0.80 | MAPT (0.46) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL5104907 | 0.79 | PPARG (0.42) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL5100830 | 0.78 | PPARA (0.53) | PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL5820210 | 0.78 | PPARG (0.49) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL5107504 | 0.76 | MAPT (0.46) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL5107495 | 0.76 | MAPT (0.46) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL5140361 | 0.76 | MAPT (0.46) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL5107356 | 0.76 | PPARG (0.69) | PPARGPPARA | |
| SCHEMBL14265753 | 0.76 | PPARG (0.69) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030914-A1 | SALTS OF BENZOTHIAZINE AND BENZOXAZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-04-18 | — | — | WO | claimed |