Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.49 |
| ▸ | PPARA | Q07869 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14265753 | 0.85 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL5107356 | 0.85 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL7693289 | 0.82 | TSHR (0.43) | PPARGPPARAMAPTLMNARXFP1 | |
| SCHEMBL14265752 | 0.80 | PPARG (0.58) | PPARGPPARAMAPTLMNARXFP1 | |
| SCHEMBL5107710 | 0.80 | PPARG (0.58) | PPARGPPARAMAPTLMNARXFP1 | |
| SCHEMBL5107137 | 0.80 | PPARG (0.58) | PPARGPPARAMAPTLMNARXFP1 | |
| SCHEMBL5104423 | 0.79 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL5107151 | 0.79 | PPARG (0.57) | PPARGPPARAMAPTLMNARXFP1 | |
| N-Benzylmethylamine SCHEMBL7525090 | 0.79 | PPARG (0.61) | PPARGPPARAPPARD | |
| Tromethamine SCHEMBL7522757 | 0.79 | PPARG (0.61) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006082495-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | disclosed |