Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820210 | 0.82 | PPARG (0.49) | TSHRLMNAMAPTRXFP1PPARG | |
| SCHEMBL5101223 | 0.81 | TSHR (0.39) | TSHRLMNAMAPTRXFP1PPARG | |
| SCHEMBL5112766 | 0.79 | PPARG (0.49) | TSHRLMNAMAPTRXFP1PPARG | |
| SCHEMBL5100773 | 0.78 | PPARG (0.41) | TSHRLMNAMAPTRXFP1PPARG | |
| SCHEMBL5104081 | 0.77 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL27580644 | 0.77 | MAPT (0.41) | TSHRLMNAMAPTRXFP1PPARG | |
| SCHEMBL5107356 | 0.77 | PPARG (0.69) | PPARGPPARA | |
| SCHEMBL14265753 | 0.77 | PPARG (0.69) | PPARGPPARA | |
| SCHEMBL5443755 | 0.76 | TSHR (0.48) | TSHRLMNAMAPTRXFP1PPARG | |
| SCHEMBL6317107 | 0.76 | MAPT (0.43) | TSHRLMNAMAPTRXFP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030914-A1 | SALTS OF BENZOTHIAZINE AND BENZOXAZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-04-18 | — | — | WO | claimed |