Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | GRM5 | P41594 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484962 | 0.89 | FABP6 (0.55) | FABP6MAOBGRM5MAOAALDH1A1 | |
| SCHEMBL569174 | 0.85 | MAOB (0.64) | MAOBGRM5MAOAALDH1A1NPC1 | |
| SCHEMBL29758920 | 0.85 | MAOB (0.64) | MAOBGRM5MAOAALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL27916588 | 0.84 | MAOB (0.62) | MAOBGRM5MAOAALDH1A1NPC1 | |
| SCHEMBL3152242 | 0.81 | MEN1 (0.59) | FABP6MAOBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL16789730 | 0.78 | MAOB (0.50) | FABP6MAOBGRM5MAOAALDH1A1 | |
| SCHEMBL10508276 | 0.78 | FABP6 (0.50) | FABP6MAOBGRM5ALDH1A1KDM4E | |
| SCHEMBL2981516 | 0.78 | MAOB (0.74) | MAOBGRM5MAOAALDH1A1KDM4E | |
| SCHEMBL4476431 | 0.78 | MAOB (0.50) | MAOBGRM5MAOAALDH1A1KDM4E | |
| SCHEMBL10434491 | 0.78 | KDM4E (0.51) | FABP6MAOBGRM5ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110791483-B | Short-chain reductase and preparation method and application thereof | 西南交通大学 | 2022-11-29 | — | — | CN | claimed |
| CN-110791483-A | Short-chain reductase and preparation method and application thereof | 西南交通大学 | 2020-02-14 | — | — | CN | claimed |
| US-10092786-B2 | Fire extinguishing composition comprising aldoketones compound | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) | 2018-10-09 | — | — | US | claimed |
| US-20160332016-A1 | Fire Extinguishing Composition Comprising Aldoketones Compound | NANO FIRE, LLC | 2016-11-17 | — | — | US | claimed |
| US-4992564-A | Preparation of 6-substituted 4-chromanones | MALLINCKRODT, INC. (US) | 1991-02-12 | — | — | US | claimed |
| US-4918203-A | Preparation of 6-substituted 4-chromanones | MALLINCKRODT INC. | 1990-04-17 | — | — | US | claimed |
| EP-0228172-B1 | PREPARATION OF 6-SUBSTITUTED 4-CHROMANONES | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1990-03-07 | — | — | EP | claimed |
| EP-0168006-B1 | PROCESS FOR PREPARING 3-(4-FLUOROPHENOXY)PROPIONITRILE AND A PROCESS FOR PREPARING 6-FLUORO-4-CHROMANONE USING 3-(4-FLUOROPHENOXY)PROPIONITRILE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-12-27 | — | — | EP | claimed |
| EP-0179570-B1 | REGENERATION OF 6-FLUORO-4-CHROMANONE FROM 6-FLUORO-4-UREIDOCHROMAN-4-CARBOXYLIC ACID | PFIZER INC. (US) | 1988-08-03 | — | — | EP | claimed |
| EP-0228172-A1 | Preparation of 6-substituted 4-chromanones | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1987-07-08 | — | — | EP | claimed |
| US-4625042-A | Process for preparing 6-fluoro-4-chromanone using 3-(4-fluorophenoxy)propionitrile | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-11-25 | — | — | US | claimed |
| EP-0179570-A1 | Regeneration of 6-fluoro-4-chromanone from 6-fluoro-4-ureidochroman-4-carboxylic acid | PFIZER INC. (US) | 1986-04-30 | — | — | EP | claimed |
| EP-0111387-B1 | REGENERATION OF 6-FLUORO-4-CHROMANONE FROM BY-PRODUCTS IN THE SYNTHESIS OF SORBINIL | PFIZER INC. (US) | 1986-04-09 | — | — | EP | claimed |
| EP-0168006-A2 | Process for preparing 3-(4-Fluorophenoxy)propionitrile and a process for preparing 6-fluoro-4-chromanone using 3-(4-fluorophenoxy)propionitrile | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-01-15 | — | — | EP | claimed |
| US-4551542-A | Regeneration of 6-fluoro-4-chromanone from 6-fluoro-4-ureidochroman-4-carboxylic acid | PFIZER INC. (US) | 1985-11-05 | — | — | US | claimed |
| EP-0111387-A1 | Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil | PFIZER INC. (US) | 1984-06-20 | — | — | EP | claimed |
| US-4431828-A | Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil | PFIZER INC. (US) | 1984-02-14 | — | — | US | claimed |
| JP-61022058-A | — | — | None | — | — | JP | disclosed |
| US-4130714-A | SPIRO CHROMANS OR THIOCHROMANS | PFIZER INC. (US) | 1978-12-19 | — | — | US | disclosed |
| US-4117230-A | ANTIDIABETIC AGENTS | PFIZER INC. (US) | 1978-09-26 | — | — | US | disclosed |