Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 12/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTGFR | P43088 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987986 | 0.80 | ACSS2 (0.47) | ACSS2BRD4 | |
| SCHEMBL6785980 | 0.75 | TDP1 (0.47) | ACSS2BRD4HTTSMN1; SMN2HPGD | |
| SCHEMBL7984945 | 0.72 | TP53 (0.47) | BRD4HPGD | |
| SCHEMBL192206 | 0.71 | GAA (0.46) | PPARG | |
| SCHEMBL192205 | 0.71 | GAA (0.46) | PPARG | |
| SCHEMBL23564593 | 0.71 | GAA (0.46) | PPARG | |
| SCHEMBL7480954 | 0.68 | ESR2 (0.41) | BRD4 | |
| SCHEMBL30847402 | 0.68 | USP30 (0.39) | SMN1; SMN2 | |
| SCHEMBL12158 | 0.68 | USP30 (0.39) | SMN1; SMN2 | |
| SCHEMBL6224033 | 0.67 | BRD4 (0.44) | BRD4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016327-A1 | BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS NEUTROPHIL INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |