Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080739 | 1.00 | ELANE (0.35) | ELANECCR5LMNASTAT3HTT | |
| SCHEMBL5969107 | 0.85 | CCR5 (0.42) | ELANECCR5LMNAHTTALDH1A1 | |
| SCHEMBL1315087 | 0.85 | CCR5 (0.38) | ELANECCR5LMNAHTTALDH1A1 | |
| SCHEMBL1315086 | 0.85 | CCR5 (0.38) | ELANECCR5LMNAHTTALDH1A1 | |
| SCHEMBL4016266 | 0.85 | CCR5 (0.42) | ELANECCR5LMNAHTTALDH1A1 | |
| SCHEMBL18227196 | 0.83 | ALOX5AP (0.38) | ELANECCR5LMNAALDH1A1RAB9A | |
| Methylsulfanylmethane SCHEMBL6111453 | 0.82 | CCR5 (0.39) | ELANECCR5LMNAHTTALDH1A1 | |
| SCHEMBL14090693 | 0.82 | CYP19A1 (0.39) | ELANEADRA1DADRA1AADRA1BCYP19A1 | |
| SCHEMBL5969600 | 0.81 | FOLH1 (0.48) | ELANEALDH1A1PTGER1 | |
| SCHEMBL2454673 | 0.81 | CYP19A1 (0.43) | RAB9ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006258-A1 | AZOLIDINES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |