SCHEMBL7693544

SCHEMBL7693544

C=C(C)CC(=NO)C(C)=O

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 2/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7693540 1.00 HTT (0.39) HTTALDH1A1TSHRCTDSP1NPSR1
SCHEMBL7696492 0.75 ALDH1A1 (0.36) ALDH1A1
SCHEMBL7696495 0.75 ALDH1A1 (0.36) ALDH1A1
SCHEMBL11273548 0.73
SCHEMBL7697883 0.72 KMT2A (0.31) ALDH1A1KMT2A
SCHEMBL7697882 0.72 KMT2A (0.31) ALDH1A1KMT2A
SCHEMBL3400128 0.70
SCHEMBL12942878 0.70
SCHEMBL3399929 0.70
SCHEMBL10563824 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6344589-B1 BIS/OXIMES FROM ACETOACETIC ESTERS BASF AKTIENGESELLSCHAFT (DE) 2002-02-05 US claimed
US-6417388-B1 REARRANGEMENT USING BASIC OR ISOMERIZATION CATALYST BASF AKTIENGESELLSCHAFT (DE) 2002-07-09 US disclosed
US-6344589-B1 BIS/OXIMES FROM ACETOACETIC ESTERS BASF AKTIENGESELLSCHAFT (DE) 2002-02-05 US disclosed
EP-1131284-A1 METHOD AND INTERMEDIATE PRODUCTS FOR PRODUCING BIS(OXIM)MONOETHERS BASF AKTIENGESELLSCHAFT (DE) 2001-09-12 EP disclosed
WO-2000031024-A1 METHOD AND INTERMEDIATE PRODUCTS FOR PRODUCING BIS(OXIM)MONOETHERS BASF AKTIENGESELLSCHAFT (DE) 2000-06-02 WO disclosed