Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 15/20 | 0.48 |
| ▸ | AKT2 | P31751 | 15/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25391 | 0.77 | F2RL1 (0.58) | AKT1AKT2F2RL1ALPGAKR1B1 | |
| SCHEMBL7467961 | 0.74 | AKT1 (0.56) | AKT1AKT2F2RL1AKR1B1 | |
| SCHEMBL11245977 | 0.67 | AKR1B1 (0.71) | ALPGAKR1B1RXFP1 | |
| SCHEMBL21500652 | 0.67 | F2RL1 (0.56) | AKT1AKT2F2RL1 | |
| SCHEMBL361086 | 0.65 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL15050025 | 0.65 | AKT1 (0.58) | AKT1AKT2F2RL1 | |
| SCHEMBL15071152 | 0.65 | F2RL1 (0.75) | F2RL1 | |
| Hydrochloric Acid SCHEMBL360472 | 0.65 | AKT1 (0.98) | AKT1AKT2 | |
| SCHEMBL5348158 | 0.64 | AKT1 (0.60) | AKT1AKT2 | |
| SCHEMBL7683359 | 0.64 | CDK2 (0.59) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |