Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1211011 | 1.00 | G6PD (0.41) | G6PDTLR9STAT3GAACTSK | |
| SCHEMBL1211008 | 1.00 | G6PD (0.41) | G6PDTLR9STAT3GAACTSK | |
| SCHEMBL7697212 | 0.91 | G6PD (0.47) | G6PDTLR9STAT3GAACTSK | |
| SCHEMBL7694213 | 0.91 | G6PD (0.47) | G6PDTLR9STAT3GAACTSK | |
| SCHEMBL7694210 | 0.91 | G6PD (0.47) | G6PDTLR9STAT3GAACTSK | |
| SCHEMBL17735725 | 0.85 | KMT2A (0.43) | G6PDTLR9STAT3GAACTSK | |
| SCHEMBL28420820 | 0.85 | G6PD (0.42) | G6PDTLR9STAT3GAACTSK | |
| SCHEMBL8553253 | 0.83 | CA1 (0.41) | G6PDTLR9STAT3GAACTSK | |
| SCHEMBL4573458 | 0.83 | G6PD (0.41) | G6PDTLR9STAT3GAACTSK | |
| SCHEMBL4573464 | 0.83 | G6PD (0.41) | G6PDTLR9STAT3GAACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344179-B1 | BIND TO DOPAMINE TRANSPORTER WITH HIGH AFFINITY AND SELECTIVITY; USEFUL AS DIAGNOSTIC AND THERAPEUTIC AGENTS; CONTAINING RADIOACTIVE ISOMERS F18 OR 19; PET SCANNING | EMORY UNIVERSITY | 2002-02-05 | — | — | US | disclosed |
| WO-2000064490-A1 | FLUOROALKENYL NORTROPANES | EMORY UNIVERSITY (US) | 2000-11-02 | — | — | WO | disclosed |