Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29022484 | 0.78 | GAA (0.39) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL539517 | 0.75 | GAA (0.50) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL7064589 | 0.75 | GAA (0.50) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL4959894 | 0.75 | MAPT (0.41) | ALDH1A1LMNAHSD17B10NPC1HPGD | |
| SCHEMBL29286220 | 0.74 | GAA (0.39) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL1578569 | 0.74 | PKM (0.41) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL26227683 | 0.74 | GAA (0.50) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL5232150 | 0.73 | — | — | |
| SCHEMBL20915122 | 0.73 | GAA (0.48) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL191649 | 0.73 | CA12 (0.41) | GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344537-B1 | RUBBER COMPOSITION WITH TWO THIIRANES AND PROTECTED GROUP WITH CARBONYL | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2002-02-05 | — | — | US | claimed |
| CN-118515596-A | Solid forms and methods of making fused tricyclic compounds, including methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-112437685-B | Solid forms and methods of making fused tricyclic compounds, including methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-118239948-A | Solid forms and methods of making fused tricyclic compounds, including methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-117946107-A | Solid forms and methods of making fused tricyclic compounds, including methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-3134402-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2017-03-01 | — | — | EP | disclosed |
| WO-2015162075-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-10-29 | — | — | WO | disclosed |
| US-6344537-B1 | RUBBER COMPOSITION WITH TWO THIIRANES AND PROTECTED GROUP WITH CARBONYL | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2002-02-05 | — | — | US | disclosed |
| US-4410688-A | POLYAMIDES FROM DIAMINOCARBOXYLIC ACIDS | ALLIED CORPORATION (US) | 1983-10-18 | — | — | US | disclosed |
| US-4360646-A | Preparation of lysine based macromolecular highly branched homogeneous compound | ALLIED CORPORATION (US) | 1982-11-23 | — | — | US | disclosed |
| US-4289872-A | SURFACE MODIFYING AGENTS, METAL CHELATING AGENTS, SUBSTRATES FOR DRUGS | ALLIED CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |