Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.64 |
| ▸ | PIM1 | P11309 | 3/20 | 0.61 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.61 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.60 |
| ▸ | MGAM | O43451 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SI | P14410 | 1/20 | 0.58 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694244 | 1.00 | HPGD (0.67) | HPGDPTPN1MAOAMAOBAKR1B1 | |
| SCHEMBL7694242 | 1.00 | HPGD (0.67) | HPGDPTPN1MAOAMAOBAKR1B1 | |
| SCHEMBL7694250 | 1.00 | HPGD (0.67) | HPGDPTPN1MAOAMAOBAKR1B1 | |
| SCHEMBL7698701 | 0.89 | HPGD (0.70) | HPGDPTPN1MAOAMAOBAKR1B1 | |
| SCHEMBL7696992 | 0.89 | PIM1 (0.65) | HPGDPTPN1MAOAMAOBAKR1B1 | |
| SCHEMBL7698706 | 0.89 | HPGD (0.70) | HPGDPTPN1MAOAMAOBAKR1B1 | |
| SCHEMBL7693214 | 0.89 | PIM1 (0.72) | HPGDPTPN1MAOAMAOBAKR1B1 | |
| SCHEMBL7693216 | 0.89 | PIM1 (0.72) | HPGDPTPN1MAOAMAOBAKR1B1 | |
| SCHEMBL7698704 | 0.89 | HPGD (0.70) | HPGDPTPN1MAOAMAOBAKR1B1 | |
| SCHEMBL7698700 | 0.89 | HPGD (0.70) | HPGDPTPN1MAOAMAOBAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002050024-A2 | THIAZOLIDINEDIONES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-06-27 | — | — | WO | claimed |