Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696853 | 0.93 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDGAATP53 | |
| SCHEMBL7704674 | 0.90 | MAPT (0.69) | ALDH1A1MAPTHPGDGAATP53 | |
| SCHEMBL7700072 | 0.90 | MAPT (0.62) | ALDH1A1MAPTHPGDGAATP53 | |
| SCHEMBL7698779 | 0.89 | MAPT (0.56) | ALDH1A1MAPTHPGDGAATP53 | |
| SCHEMBL7697506 | 0.89 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDGAATP53 | |
| SCHEMBL7694777 | 0.87 | MAPT (0.58) | ALDH1A1MAPTHPGDGAATP53 | |
| SCHEMBL7699874 | 0.84 | MAPT (0.66) | ALDH1A1MAPTHPGDGAATP53 | |
| SCHEMBL7700945 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDGAAKDM4E | |
| SCHEMBL7700870 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDGAATP53 | |
| SCHEMBL7696343 | 0.82 | MAPT (0.73) | ALDH1A1MAPTHPGDGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |