Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5600967 | 0.92 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL7015617 | 0.87 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL7016287 | 0.86 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5866841 | 0.86 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL7015261 | 0.83 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL7020399 | 0.83 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL7016690 | 0.83 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL7015606 | 0.82 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL7016136 | 0.82 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL7019418 | 0.81 | CRHR1 (0.45) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492520-B1 | COMPOUNDS (I) ARE CORTICOTROPIN RELEASING FACTOR (HORMONE) CRF (CRH) ANTAGONISTS. | PFIZER INC | 2002-12-10 | — | — | US | disclosed |