Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 10/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.51 |
| ▸ | KDR | P35968 | 5/20 | 0.45 |
| ▸ | MET | P08581 | 5/20 | 0.45 |
| ▸ | AURKA | O14965 | 4/20 | 0.45 |
| ▸ | TEK | Q02763 | 4/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693978 | 0.93 | ADRB3 (0.58) | ADRB1ADRB3KDRMETAURKA | |
| SCHEMBL7692667 | 0.93 | ADRB3 (0.50) | ADRB1ADRB3KDRMETAURKA | |
| SCHEMBL7687729 | 0.92 | ADRB3 (0.49) | ADRB1ADRB3METCYP2D6ADRB2 | |
| SCHEMBL7692653 | 0.92 | ADRB3 (0.51) | ADRB1ADRB3KDRMETAURKA | |
| SCHEMBL7692899 | 0.90 | ADRB3 (0.50) | ADRB1ADRB3MET | |
| SCHEMBL7689875 | 0.90 | ADRB3 (0.52) | ADRB1ADRB3KDRMETAURKA | |
| SCHEMBL7693508 | 0.90 | ADRB3 (0.49) | ADRB1ADRB3MET | |
| SCHEMBL7693483 | 0.90 | ADRB3 (0.57) | ADRB1ADRB3KDRMETAURKA | |
| SCHEMBL7695730 | 0.89 | ADRB3 (0.46) | ADRB1ADRB3METADRB2 | |
| SCHEMBL6479456 | 0.89 | ADRB3 (0.58) | ADRB1ADRB3METADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |