Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.49 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692667 | 0.94 | ADRB3 (0.50) | ADRB3ADRB1METADRB2CA12 | |
| SCHEMBL7693978 | 0.93 | ADRB3 (0.58) | ADRB3ADRB1METADRB2CA12 | |
| SCHEMBL7692899 | 0.93 | ADRB3 (0.50) | ADRB3ADRB1METEGLN1 | |
| SCHEMBL7694489 | 0.92 | ADRB1 (0.51) | ADRB3ADRB1METADRB2CYP2D6 | |
| SCHEMBL7693508 | 0.92 | ADRB3 (0.49) | ADRB3ADRB1METEGLN1 | |
| SCHEMBL7692653 | 0.91 | ADRB3 (0.51) | ADRB3ADRB1MET | |
| SCHEMBL7695730 | 0.91 | ADRB3 (0.46) | ADRB3ADRB1METADRB2CA12 | |
| SCHEMBL7689875 | 0.89 | ADRB3 (0.52) | ADRB3ADRB1MET | |
| SCHEMBL6479456 | 0.89 | ADRB3 (0.58) | ADRB3ADRB1METADRB2 | |
| SCHEMBL6479461 | 0.89 | ADRB3 (0.58) | ADRB3ADRB1METADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | claimed |
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |