Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.45 |
| ▸ | PDE4A | P27815 | 11/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711411 | 0.99 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4CCYP3A4 | |
| SCHEMBL8711347 | 0.90 | PDE4D (0.40) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8712435 | 0.87 | PDE4B (0.42) | PDE4DPDE4APDE4BPDE4CCYP3A4 | |
| Hydrochloric Acid SCHEMBL8707877 | 0.87 | PDE4A (0.44) | PDE4DPDE4APDE4BPDE4CS1PR1 | |
| SCHEMBL8712205 | 0.86 | HTR2C (0.42) | PDE4DPDE4APDE4BPDE4CLMNA | |
| SCHEMBL7696958 | 0.85 | PDE4B (0.49) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7698977 | 0.84 | PDE4B (0.42) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8709437 | 0.82 | PDE4A (0.46) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7692927 | 0.81 | PDE4B (0.44) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7698605 | 0.81 | PDE4B (0.42) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |