Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713416 | 0.92 | HTR2C (0.42) | HTR2CHTR2BPDE4BPDE4DLMNA | |
| SCHEMBL8714432 | 0.86 | HTR2C (0.49) | HTR2CHTR2BPDE4BPDE4DPDE4A | |
| SCHEMBL7695166 | 0.86 | PDE4D (0.45) | PDE4BPDE4DLMNAPDE4APDE4C | |
| SCHEMBL8711411 | 0.85 | PDE4D (0.44) | PDE4BPDE4DLMNAPDE4APDE4C | |
| SCHEMBL8707491 | 0.82 | HTR2C (0.49) | HTR2CHTR2BPDE4BPDE4DPDE4A | |
| SCHEMBL8712925 | 0.78 | PDE4B (0.44) | HTR2CHTR2BPDE4BPDE4DPDE4A | |
| SCHEMBL8712435 | 0.78 | PDE4B (0.42) | HTR2CHTR2BPDE4BPDE4DLMNA | |
| SCHEMBL8711347 | 0.78 | PDE4D (0.40) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8712036 | 0.77 | RAB9A (0.54) | HTR2CPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8713534 | 0.77 | LMNA (0.48) | HTR2CHTR2BLMNACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |