Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2447686 | 0.85 | ROCK1 (0.51) | ROCK1DRD2LMNAMAPTALDH1A1 | |
| SCHEMBL2467491 | 0.79 | ROCK1 (0.49) | ROCK1DRD2LMNAMAPTALDH1A1 | |
| SCHEMBL31110066 | 0.76 | ROCK1 (0.51) | ROCK1DRD2LMNAMAPTALDH1A1 | |
| SCHEMBL2312739 | 0.76 | ROCK1 (0.51) | ROCK1DRD2LMNAMAPTALDH1A1 | |
| SCHEMBL6653019 | 0.76 | ROCK1 (0.54) | ROCK1DRD2LMNAMAPTALDH1A1 | |
| SCHEMBL27966687 | 0.76 | ROCK1 (0.51) | ROCK1DRD2LMNAMAPTALDH1A1 | |
| SCHEMBL27872559 | 0.74 | ROCK1 (0.49) | ROCK1DRD2LMNAMAPTALDH1A1 | |
| SCHEMBL27872558 | 0.74 | DRD2 (0.57) | ROCK1DRD2LMNAMAPTALDH1A1 | |
| SCHEMBL23579413 | 0.74 | ROCK1 (0.46) | ROCK1DRD2LMNAMAPTALDH1A1 | |
| SCHEMBL29974269 | 0.74 | ROCK1 (0.46) | ROCK1DRD2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403588-B1 | PHOSPHATIDYLINOSITOL 3 KINASE (PI3K) INHIBITING ACTIVITY WHICH ARE USEFUL AS MEDICAMENTS, MORE PARTICULARLY AS ANTITUMOR AGENT | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |