Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB2 | Q9UBS0 | 6/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696775 | 0.90 | RPS6KB2 (0.53) | RPS6KB2ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL7690215 | 0.85 | RPS6KB2 (0.60) | RPS6KB2ABCG2MEN1KMT2ARAB9A | |
| SCHEMBL7695652 | 0.85 | RPS6KB2 (0.60) | RPS6KB2ABCG2MEN1KMT2APDE5A | |
| SCHEMBL6239609 | 0.82 | MAPT (0.51) | ABCG2MEN1KMT2APDE5AMAPT | |
| SCHEMBL7696931 | 0.81 | RPS6KB2 (0.55) | RPS6KB2ABCG2MEN1KMT2ARAB9A | |
| SCHEMBL7691382 | 0.81 | ABCG2 (0.61) | RPS6KB2ABCG2MEN1KMT2ARAB9A | |
| SCHEMBL6239210 | 0.80 | MAPT (0.47) | RPS6KB2MEN1KMT2AEPHX2RAB9A | |
| SCHEMBL7697772 | 0.79 | RPS6KB2 (0.58) | RPS6KB2ABCG2MEN1KMT2APDE5A | |
| SCHEMBL7694559 | 0.78 | RPS6KB2 (0.51) | RPS6KB2MEN1KMT2ARAB9APDE5A | |
| SCHEMBL7697783 | 0.78 | RPS6KB2 (0.57) | RPS6KB2ABCG2MEN1KMT2APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |