SCHEMBL7696097

SCHEMBL7696097

CCCCCOc1ccc(C(F)(F)F)cc1N(Cc1ccccc1)CC(O)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 18/20 0.52
PTGDR2 Q9Y5Y4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5207853 0.87 CETP (0.47) CETP
SCHEMBL7030475 0.80 CETP (0.54) CETP
SCHEMBL3318026 0.78 CETP (0.61) CETP
SCHEMBL5214560 0.77 CETP (0.57) CETP
SCHEMBL5207968 0.74 PPARG (0.41) CETP
SCHEMBL6444570 0.67 CETP (0.77) CETP
SCHEMBL3318029 0.67 CETP (0.71) CETP
SCHEMBL5207873 0.67 CETP (0.78) CETP
SCHEMBL2841893 0.67 CETP (0.54) CETP
SCHEMBL3322740 0.66 CETP (0.77) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020165232-A1 Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity SIKORSKI JAMES A (US) 2002-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165232-A1 Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity CETP, DBI, PLTP CETP 1/4885PTGDR2 3719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.