Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690593 | 0.99 | SIGMAR1 (0.50) | SIGMAR1SLC6A3NPC1HTTRAB9A | |
| SCHEMBL7691330 | 0.99 | SIGMAR1 (0.50) | SIGMAR1SLC6A3NPC1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL6891188 | 0.79 | NPC1 (0.52) | SIGMAR1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10862300 | 0.77 | DPP7 (0.53) | SIGMAR1SLC6A3RAB9ADPP7 | |
| SCHEMBL10861265 | 0.75 | DPP7 (0.51) | SIGMAR1SLC6A3RAB9ADPP7 | |
| SCHEMBL27779884 | 0.74 | SIGMAR1 (0.47) | SIGMAR1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL4338287 | 0.73 | SIGMAR1 (0.59) | SIGMAR1SLC6A3RAB9AABCB1 | |
| SCHEMBL4333079 | 0.73 | SIGMAR1 (0.59) | SIGMAR1SLC6A3RAB9AABCB1 | |
| SCHEMBL6890586 | 0.71 | SIGMAR1 (0.47) | SIGMAR1NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL6890587 | 0.71 | SIGMAR1 (0.47) | SIGMAR1NPC1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012185-A1 | PROCESS FOR PREPARING 2,3-DIAMINOPROPANOLS AND SYNTHESIS OF OTHER COMPOUNDS USING 2,3-DIAMINOPROPANOLS | CHEMBIONEX CO., LTD. (KR) | 2002-02-14 | — | — | WO | disclosed |