SCHEMBL7696494

SCHEMBL7696494

CCOC(=O)C(Cc1ccc(OCCNCC2c3ccc(Cc4ccccc4)cc3CCc3cc(Cc4ccccc4)ccc32)cc1)OCC

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.49
PPARG P37231 10/20 0.47
PPARA Q07869 6/20 0.45
PPARD Q03181 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6716080 0.83 PPARG (0.67) PPARGPPARAPPARD
SCHEMBL7802178 0.81 PPARG (0.46) LTA4HPPARGPPARAPPARD
SCHEMBL6719343 0.81 PPARG (0.67) LTA4HPPARGPPARAPPARD
SCHEMBL6719472 0.81 PPARG (0.74) LTA4HPPARGPPARAPPARD
SCHEMBL6724423 0.80 PPARG (0.66) LTA4HPPARGPPARAPPARD
SCHEMBL6724220 0.80 PPARG (0.66) LTA4HPPARGPPARAPPARD
SCHEMBL6714521 0.79 PPARG (0.65) LTA4HPPARGPPARAPPARD
SCHEMBL7696496 0.79 PPARG (0.44) PPARGPPARAPPARD
SCHEMBL7788160 0.78 PPARG (0.56) PPARGPPARAPPARD
SCHEMBL6719224 0.78 PPARG (0.65) LTA4HPPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6407127-B2 3-(4-(2-(5H-DIBENZO(A,D)CYCLOHEPTEN-5-YLOXY)-ETHOXYL-PHENYL)-2 -ETHOXY-PROPIONIC ACID ETHYL ESTER AS ANTIDIABETIC AGENTS AND TO TREAT OBESITY NOVO NORDISK A/S (DK) 2002-06-18 US disclosed
US-20010031764-A1 Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors(PPAR) JEPPESEN LONE (DK) 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031764-A1 Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors(PPAR) PPARG, PPARA, PPARD LTA4H 1802/4885PPARG 1/4885PPARA 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.