Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788160 | 0.86 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL7696494 | 0.81 | LTA4H (0.49) | PPARGPPARAPPARDLTA4H | |
| SCHEMBL6724160 | 0.80 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL7802180 | 0.79 | PPARG (0.42) | PPARGPPARAPPARDKLKB1 | |
| SCHEMBL6717199 | 0.79 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL6715873 | 0.79 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL6717210 | 0.79 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL6724329 | 0.79 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL6717686 | 0.78 | PPARG (0.67) | PPARGPPARAPPARDLTA4H | |
| SCHEMBL6724046 | 0.78 | PPARG (0.57) | PPARGPPARAPPARDLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031764-A1 | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors(PPAR) | JEPPESEN LONE (DK) | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031764-A1 | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors(PPAR) | PPARG, PPARA, PPARD | PPARG 1/4885PPARA 2/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.