Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.51 |
| ▸ | CHRNG | P07510 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696569 | 1.00 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL2053238 | 0.83 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL157418 | 0.83 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL30866537 | 0.83 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL14836448 | 0.83 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL8441154 | 0.83 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL31019629 | 0.83 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL14875533 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL1757177 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL11911578 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486876-A | Compounds as inhibitors of Akt kinase | 正大天晴药业集团股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20230357242-A1 | COMPOUND AS AKT KINASE INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-11-09 | — | — | US | disclosed |
| EP-4223754-A1 | COMPOUND AS AKT KINASE INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-08-09 | — | — | EP | disclosed |
| CN-116194452-A | Compounds as inhibitors of Akt kinase | 正大天晴药业集团股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| WO-2002058635-A2 | NICOTINE IMMUNOGENS AND ANTIBODIES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-08-01 | — | — | WO | disclosed |
| US-4243605-A | RADIOIMMUNOASSAY, LABELS | UNION CARBIDE CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-4115539-A | RADIOIMMUNOASSAY, REACTION PRODUCT WITH ISOCYANATES | UNION CARBIDE CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357242-A1 | COMPOUND AS AKT KINASE INHIBITOR | AKT2, MTOR, AKT1 | CHRNB2 4751/4885CHRNA4 4842/4885CHRNA7 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.