Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 6/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | RHOA | P61586 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | NPM1 | P06748 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696400 | 0.87 | PDGFRB (0.76) | PDGFRBPDGFRANPC1RAB9ARHOA | |
| SCHEMBL6213413 | 0.85 | PDGFRB (0.74) | PDGFRBPDGFRANPC1RAB9ARHOA | |
| SCHEMBL7691917 | 0.85 | PDGFRB (0.56) | PDGFRBPDGFRARHOAMEN1KMT2A | |
| SCHEMBL7693969 | 0.84 | PDGFRB (0.63) | PDGFRBPDGFRANPC1RAB9ARHOA | |
| SCHEMBL7695581 | 0.84 | PDGFRB (0.59) | PDGFRBPDGFRANPC1RAB9ARHOA | |
| SCHEMBL7695393 | 0.84 | PDGFRB (0.59) | PDGFRBPDGFRANPC1RAB9ARHOA | |
| SCHEMBL7696819 | 0.84 | PDGFRB (0.68) | PDGFRBPDGFRANPC1RAB9ARHOA | |
| SCHEMBL6216430 | 0.84 | PDGFRB (0.72) | PDGFRBPDGFRANPC1RAB9ARHOA | |
| SCHEMBL7692632 | 0.82 | PDGFRB (0.60) | PDGFRBPDGFRANPC1RAB9ARHOA | |
| SCHEMBL10197523 | 0.81 | PDGFRB (0.68) | PDGFRBPDGFRANPC1RAB9ARHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |