Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1247453 | 1.00 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL593115 | 1.00 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL8006097 | 1.00 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL51018 | 0.95 | — | — | |
| SCHEMBL4257983 | 0.89 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL219996 | 0.89 | — | — | |
| SCHEMBL2899136 | 0.86 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL5105617 | 0.86 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL19136736 | 0.84 | — | — | |
| SCHEMBL3680436 | 0.83 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012204-A1 | 2H-BENZOTRIAZOLE UV ABSORBERS SUBSTITUTED WITH 1,1-DIPHENYLALKYL GROUPS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-14 | — | — | WO | disclosed |