Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.93 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637104 | 0.96 | HTR1A (1.00) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL6637107 | 0.96 | HTR1A (1.00) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL7523131 | 0.94 | HTR1A (0.81) | HTR1ASLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL7692311 | 0.90 | HTR1A (0.75) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6636012 | 0.89 | HTR1A (0.86) | HTR1ASLC6A4 | |
| SCHEMBL6635879 | 0.89 | HTR1A (0.86) | HTR1ASLC6A4 | |
| SCHEMBL6635151 | 0.89 | HTR1A (0.86) | HTR1ASLC6A4 | |
| SCHEMBL7691693 | 0.87 | HTR1A (0.71) | HTR1ASLC6A4 | |
| SCHEMBL6634611 | 0.86 | HTR1A (0.81) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6636129 | 0.84 | HTR1A (0.78) | HTR1ASLC6A4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337326-B1 | CENTRAL NERVOUS SYSTEM ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION | 2002-01-08 | — | — | US | claimed |
| US-6337326-B1 | CENTRAL NERVOUS SYSTEM ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION | 2002-01-08 | — | — | US | disclosed |