Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.52 |
| ▸ | PLD2 | O14939 | 8/20 | 0.49 |
| ▸ | PLD1 | Q13393 | 7/20 | 0.49 |
| ▸ | SCN1A | P35498 | 5/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4804251 | 1.00 | OPRL1 (0.52) | OPRL1PLD2PLD1SCN1ASCN5A | |
| SCHEMBL4803925 | 0.94 | PLD2 (0.55) | OPRL1PLD2PLD1 | |
| SCHEMBL4806688 | 0.92 | OPRL1 (0.54) | OPRL1PLD2PLD1SCN1ASCN5A | |
| SCHEMBL4805216 | 0.92 | PLD2 (0.59) | OPRL1PLD2PLD1SCN1ASCN5A | |
| Hydrochloric Acid SCHEMBL4806574 | 0.89 | OPRL1 (0.61) | OPRL1PLD2PLD1SCN1ASCN5A | |
| SCHEMBL4807512 | 0.86 | PLD2 (0.66) | OPRL1PLD2PLD1 | |
| SCHEMBL4804373 | 0.86 | PLD2 (0.60) | OPRL1PLD2PLD1HSD11B1 | |
| SCHEMBL4806305 | 0.85 | PLD2 (0.59) | OPRL1PLD2PLD1HSD11B1 | |
| SCHEMBL4806019 | 0.83 | OPRL1 (0.63) | OPRL1PLD2PLD1CTSS | |
| SCHEMBL4807271 | 0.83 | OPRL1 (0.67) | OPRL1PLD2PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002074763-A9 | BENZIMIDAZOL DERIVATIVES MODULATE CHEMOKINE RECEPTORS | ASTRAZENECA AB (SE) | 2002-10-24 | — | — | WO | disclosed |