Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7038087 | 0.98 | SLC18A3 (0.39) | SLC18A3MAPTMAPK1HTTNPSR1 | |
| SCHEMBL6271908 | 0.74 | MAPT (0.43) | MAPTMAPK1HTTNPSR1ESR1 | |
| SCHEMBL4019885 | 0.73 | SLC18A3 (0.42) | SLC18A3MAPTMAPK1HTTNPSR1 | |
| SCHEMBL15457811 | 0.71 | SLC18A3 (0.37) | SLC18A3MAPTMAPK1HTTNPSR1 | |
| SCHEMBL3231048 | 0.70 | L3MBTL1 (0.46) | MAPTMAPK1HTTNPSR1ESR1 | |
| SCHEMBL21276506 | 0.68 | USP30 (0.40) | SLC18A3MAPTMAPK1HTTNPSR1 | |
| SCHEMBL6621014 | 0.67 | BPTF (0.54) | SLC18A3MAPK1NOTUMMEN1KMT2A | |
| SCHEMBL16254045 | 0.67 | MAPT (0.39) | SLC18A3MAPTMAPK1HTTNPSR1 | |
| SCHEMBL2775831 | 0.66 | SMN1; SMN2 (0.41) | MAPTMAPK1HTTNPSR1ESR1 | |
| SCHEMBL2775830 | 0.66 | SMN1; SMN2 (0.41) | MAPTMAPK1HTTNPSR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008303-A | Preparation method of 1-Boc-3-hydroxyl azetidine medical intermediate | 苏州艾缇克药物化学有限公司 | 2016-10-12 | — | — | CN | claimed |
| CN-106008303-A | Preparation method of 1-Boc-3-hydroxyl azetidine medical intermediate | 苏州艾缇克药物化学有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-106008303-A | Preparation method of 1-Boc-3-hydroxyl azetidine medical intermediate | 苏州艾缇克药物化学有限公司 | 2016-10-12 | — | — | CN | disclosed |
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | disclosed |